en ورزش، تمرین و سلامتی Exercise, Training and Health مقاله مروری Review Article <div style="text-align: justify;"><strong>Background. </strong>The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has created an unprecedented and daunting challenge for humanity to survive. This has also affected the sporting events across the globe as the majority of the tournaments have been cancelled or postponed as a result. For life to return to pre-pandemic normalcy, an effective and safe vaccination program needs to be implemented, be readily accessible, widely available, and affordable at the same time.<br> <strong>Objectives. </strong>In this review, we analyze various challenges which demonstrate that COVID-19 is far from over.<br> <strong>Methods. </strong>A systematic literature search was conducted on PubMed, ScienceDirect, Medline, Google Scholar, and Scopus from the commencement of the COVID-19 pandemic to 22 June 2021. The current report is a summary of data regarding challenges faced by the COVID-19 vaccination campaign and the challenges for a transition toward normalcy, especially for big sports events.<br> <strong>Results. </strong>The current COVID-19 pandemic has likely resulted in sporting events and tournaments being canceled, postponed, or held without or with restricted spectators around the world. A combination of measures including prompt vaccination with the beneficial impact of the vaccines in reducing the severity of disease, advances in treatment, expanded use of diagnostics and better implementation of public-health policies are a necessity. Following this implementation, a transition toward normality could be expected when the mortality rate of COVID-19 simulates the average influenza statistics, with public-health measures continuing to play an important role worldwide.<br> <strong>Conclusion. </strong>The authors believe that COVID-19 will be endemic in the human population, similar to seasonal influenza and that COVID-19 vaccines will be included as an add-on to seasonal influenza vaccinations, being administered every winter for at least the next few decades. With adequate vaccination, the sporting world will be able to withstand the challenges and resume global events, returning to pre-Covid levels of normalcy.</div> Pandemic, SARS-COV-2, Mutation, Olympic Games, FIFA World Cup 0 0 http://aassjournal.com/browse.php?a_code=A-11-1719-1&slc_lang=en&sid=1 Ismail Dergaa idergaa@phcc.gov.qa 100319475328460010163 100319475328460010163 Yes PHCC, Primary Health Care Corporation, Doha, Qatar Huda Abdelrahman HAbdelrahman@phcc.gv.qa 100319475328460010164 100319475328460010164 No PHCC, Primary Health Care Corporation, Doha, Qatar Amit Varma AVarma@phcc.gov.qa 100319475328460010165 100319475328460010165 No PHCC, Primary Health Care Corporation, Doha, Qatar Narimen Yousfi 100319475328460010166 100319475328460010166 No Research Laboratory “Sport Performance Optimization”, National Centre of Medicine and Science in Sport (CNMSS), Tunis, Tunisia Amine Souissi 100319475328460010167 100319475328460010167 No Research Laboratory “Sport Performance Optimization”, National Centre of Medicine and Science in Sport (CNMSS), Tunis, Tunisia Amine Ghram 100319475328460010168 100319475328460010168 No Research Laboratory “Sport Performance Optimization”, National Centre of Medicine and Science in Sport (CNMSS), Tunis, Tunisia Ayat Samir Hammad 100319475328460010169 100319475328460010169 No Hamad Bin Khalifa University, College of Health and Life Science Eiman Rashid Musa 100319475328460010170 100319475328460010170 No HMC, Hamad Medical Corporation, PO Box 3050, Doha, Qatar Morteza Taheri 100319475328460010171 100319475328460010171 No Department of Sport Sciences, Imam Khomeini International University, Qazvin, Iran Khadijeh Irandoust 100319475328460010172 100319475328460010172 No Department of Sport Sciences, Imam Khomeini International University, Qazvin, Iran Hamdi Chtourou 100319475328460010173 100319475328460010173 No Institut Supérieur du Sport et de l’éducation physique de Sfax, Université de Sfax, Sfax, Tunisia. Activité Physique, Sport et Santé, UR18JS01, Observatoire National du Sport, Tunis, Tunisia Mohammad Mahdi Rafiei 100319475328460010174 100319475328460010174 No Depratment of exercise physiology, Faculty of Physical Education & Sport Sciences, University of Tehran, kish International Campus Mohammad Ghasemi 100319475328460010175 100319475328460010175 No Department of Sport Sciences, Imam Khomeini International University, Qazvin, Iran Shakiba Farzian 100319475328460010176 100319475328460010176 No Department of Physical Education and Sport Sciences, Islamic Azad University, Qazvin Branch, Qazvin, Iran