Annals of Applied Sport Science
تازههای علوم کاربردی ورزش
Ann Appl Sport Sci
Medical Sciences
http://aassjournal.com
1
admin
2476–4981
2322-4479
10.61186/aassjournal
en
jalali
1399
9
1
gregorian
2020
12
1
8
4
online
1
fulltext
en
The Effect of Swimming Training on Serum Levels of Sex Hormones, Antioxidant Enzymes and Oxidative Damage of DNA Ovarian Tissue in Rats with Polycyclic Ovarian Syndrome
ورزش، تمرین و سلامتی
Exercise, Training and Health
مقاله اصیل
Original Article
<div style="text-align: justify;"><strong>Background.</strong> Hormone disorders, stress-oxidative and inflammation in ovarian tissue cause no- ovulation in women with polycyclic ovarian syndrome (PCOS). Several studies have shown the role of exercises in control of sex hormones.<br>
<strong>Objectives.</strong> The aim of this study was to investigate the effect of 6 weeks of swimming training (ST) on serum levels of sex hormones, antioxidant enzymes and oxidative damage of DNA ovarian tissue in rats with PCOS.<br>
<strong>Methods.</strong> In this experimental study, 30 female Wistar rats were divided into 3 groups included control, PCO (letrozole consumption for 28 days intra- peritoneally) and PCO+ST groups. PCOS was induced with 28 days of peritoneal injection of 1 mg/kg letrozole. The ST program was included 6 weeks of ST for 20 minutes per day. At the end of the treatment period, serum levels of LH, FSH, testosterone, estradiol and progesterone, SOD, CAT, GPX, MDA and HOdG-8 in ovarian tissue were measured by ELISA method.<br>
<strong>Results.</strong> ST significantly decreased serum levels of LH, estradiol, testosterone, MDA and HOdG-8 levels (p<0.05) as well as increased SOD, CAT, and GPX enzymes of rats with PCOS (p<0.05).<br>
<strong>Conclusion.</strong> It appears that ST has antioxidant and sex hormone enhancing effects in ovarian tissue of rats with PCOS model.</div>
Polycystic Ovarian Syndrome, Training, Sex Hormones, Oxidative Stress
0
0
http://aassjournal.com/browse.php?a_code=A-11-1235-1&slc_lang=en&sid=1
Mehdi
Noura
noora.mehdi@yahoo.com
10031947532846008677
10031947532846008677
Yes
Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
Samane
Rafie
samanerafie6360@gmail.com
10031947532846008678
10031947532846008678
No
Department of Sport Physiology, Kish International Paradise, University of Tehran, Kish, Iran
Seyed Ali
Hosseini
alihoseini_57@miau.ac.ir
10031947532846008679
10031947532846008679
No
Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
Mohammad Amin
Edalatmanesh
amin.edalatmanesh@gmail.com
10031947532846008680
10031947532846008680
No
Department of Physiology, Science Faculty, Shiraz Branch, Islamic Azad University, Shiraz, Iran