en فيزيولوژی ورزشی و شاخه‌های وابسته بدان Sport Physiology and its related branches مقاله اصیل Original Article <div style="text-align: justify;"><span style="font-family:times new roman;"><strong>Background.</strong> It seems strenuous </span><span style="font-family:times new roman;">trainings</span><span style="font-family:times new roman;"> have a suppressing effect on the immune function and athletes performing such </span><span style="font-family:times new roman;">trainings</span><span style="font-family:times new roman;"> are probably prone to infectious diseases due to </span><span style="font-family:times new roman;">weakened</span><span style="font-family:times new roman;"> immune system.<br> <strong>Objectives. </strong>The aim of this study was to examine the effect of six weeks of high-intensity interval training (HIIT) with and without zinc &lrm;supplementation on serum immunoglobulin concentrations in female futsal players. </span><br> <strong><span style="font-family:times new roman;">Mthods</span></strong><span style="font-family:times new roman;"><strong>. </strong>Thirty-two female futsal players were randomly divided into 4 groups like placebo, Zinc, HIIT+Placebo &lrm;</span><span style="font-family:times new roman;">and</span><span style="font-family:times new roman;"> Zinc+HIIT. All athletes had to attend futsal-specific training 3 sessions per week. Zinc and Placebo groups took &lrm;30 mg &lrm;day&minus;1 of zinc gluconate or dextrose, respectively, and HIIT groups performed 6-10 repetitions of a 30-second running at 100% of VO2peak with &lrm;4-minutes rest between the efforts during six weeks.<br> <strong>Results. </strong>IgM levels decreased significantly in&nbsp;</span><span style="font-family:times new roman;">placebo</span><span style="font-family:times new roman;"> group (from 136.25&plusmn;34.44 to 119&plusmn;33.53, p=0.003) and Zinc group (from 143.25&plusmn;52.96 to 123.62&plusmn;50.33, p=0.005). 6 weeks of HIIT did not change the levels of IgA, IgM </span><span style="font-family:times new roman;">and</span><span style="font-family:times new roman;"> IgG significantly (p>0.05). HIIT along with Zinc augmented IgA value (from 179.75&plusmn;54.49 to 211.12&plusmn;89.22, p=0.049), significantly; It also increased IgM&lrm; and IgG levels which were not significant (p>0.05).<br> <strong>Conclusion. </strong>It can be concluded that 6 weeks of HIIT had no suppressing effect on the immune system in female futsal players; even HIIT along with Zinc supplementation improved the immune system via increasing IgA value.</span></div> Interval Training, Zinc Supplement, Immunoglobulin A, Immunoglobulin M, Immunoglobulin G. 11 19 http://aassjournal.com/browse.php?a_code=A-11-511-2&slc_lang=en&sid=1 Malihe Saeedy Malihe.Saeedy@yahoo.com‎ 10031947532846007043 10031947532846007043 No Exercise Physiology Department, Faculty of Physical Education and ‎Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran Nahid Bijeh bijeh@ferdowsi.um.ac.ir 10031947532846007044 10031947532846007044 Yes Exercise Physiology Department, Faculty of Physical Education and ‎Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran Mahtab Moazzami moazzami@um.ac.ir 10031947532846007045 10031947532846007045 No Exercise Physiology Department, Faculty of Physical Education and ‎Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran