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1- Doctoral Program in Sports Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan
2- Department of Sport Research, Japan Institute of Sports Sciences, Kita-ku, Japan
3- Laboratory of Laboratory/Sports Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
4- Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan ,
Abstract:   (674 Views)
Background. Persistent physical fatigue (PPhF) is one of the most common issues in athletes; salivary human herpes virus 6 and/or 7 (HHV-6/7) have recently attracted attention as novel microbiological markers for its assessment. Objectives: We aimed to investigate potential variabilities of salivary HHV-6/7 levels in athletes, along with traditional assessments. Methods. We conducted an observational study over two weeks including 54 healthy male university athletes (n = 44) and non-athletes (n = 10). We used a questionnaire on daily life to monitor the participants’ states and habits. The main measures were salivary HHV-6/7 and secretory immunoglobulin A (SIgA) levels, and total mood disturbance (TMD) scores in the Profile of Mood States. Results. In the questionnaire on daily life, subjective fatigue increased in the athletes (p < 0.05), while the health condition and daily habits did not change in either group (p > 0.05); accordingly, fatigue may be due to training-induced physical stressors rather than pathological events or changes in daily habits. Salivary HHV-6 levels increased only in the athletes after one week (p < 0.05), whereas salivary HHV-7 and SIgA levels, and TMD scores remained unchanged (p > 0.05). Conclusion. These findings suggested that salivary HHV-6 may be a more sensitive marker of PPhF than others.
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  • Use of salivary HHV-6 is expected to allow for earlier detection of PPhF which other markers fail to do.
  • Salivary HHV-6 levels increased independently of salivary SIgA levels; thus, the viral marker has different meaning from immune marker.

Type of Study: Original Article | Subject: Exercise, Training and Health
Received: 2021/10/4 | Accepted: 2021/01/12

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